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Results for "

ET-743

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Isotope-Labeled Compounds (1) Reactive Oxygen Species (2)
By Research Areas:	Cancer (2) Inflammation/Immunology (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-50936

Trabectedin 3 Publications Verification Ecteinascidin 743; ET-743	Reactive Oxygen Species Apoptosis	Inflammation/Immunology Cancer
Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has the potential for soft tissue sarcoma and ovarian cancer research .

HY-50936S

Trabectedin-d3 Ecteinascidin 743-d₃; ET-743-d₃	Isotope-Labeled Compounds Reactive Oxygen Species Apoptosis	Inflammation/Immunology Cancer
Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment .

HY-137787

Cyanosafracin B

Others Others

Cyanosafracin B is a starting material for synthesis of Ecteinascidin ET-743 and Phthalascidin Pt-650 .

$Cyanosafracin B$

Cyanosafracin B	Others	Others
Cyanosafracin B is a starting material for synthesis of Ecteinascidin ET-743 and Phthalascidin Pt-650 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-50936

Trabectedin 3 Publications Verification Ecteinascidin 743; ET-743	Alkaloids Structural Classification Classification of Application Fields Animals Source classification Marine natural products Other marine organisms Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species Apoptosis
Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has the potential for soft tissue sarcoma and ovarian cancer research .

HY-137787

Cyanosafracin B	Microorganisms Marine natural products Source classification	Others
Cyanosafracin B is a starting material for synthesis of Ecteinascidin ET-743 and Phthalascidin Pt-650 .

$Cyanosafracin B$

Cat. No.	Product Name	Chemical Structure

HY-50936S

Trabectedin-d3
Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment .

Trabectedin-d3

Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment .

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